The other two both males, have grown into spotted toads. They were christened Spot and Blondie. “I was absolutely thrilled when it happened,” Tizard told me. Then Cooper began to "turn off" the toxicity of toads. The poison (bufotoxin) in the toad-aga is produced in large parotid glands located closer to the back, as well as in smaller glands scattered throughout the body. Isolated in its normal state, it simply makes mammals sick. If the toad feels danger, it produces a special enzyme - bufotoxin hydrolase - which enhances the effect of the poison a hundredfold. Using CRISPR technology, Cooper edited the second batch of embryos and removed part of.
The gene encoding bufotoxin hydrolase. After the conversation, Cooper offered to look at the toads themselves. To do this, we traveled deeper into the AAHL, passing through several sealed doors and Russia WhatsApp Number List security levels. We all put on protective suits over our clothes and shoe covers over our shoes. Cooper sprayed my recorder with some kind of disinfectant. The sign on the door read: “Quarantine zone. Violators face fines." I decided it was best not to tell The Odin about my own, far less safe, gene-editing adventures. Behind the doors was something like a sterile menagerie, filled with animals in enclosures of various sizes.
It smelled of hospital and petting zoo at the same time. Poison-free toads hopped around a few cages around a plastic tank. There were about a dozen of them, about ten weeks old, and each 7-8 cm long. “See how active they are,” Cooper said. The tank contained everything a man thought a toad might need: artificial plants, a bath of water, a lamp. I thought of Mr. Toad's house, "full of every modern convenience," from Kenneth Graham's fairy tale The Wind in the Willows. One of the toads stuck out its tongue and grabbed a cricket. “They eat literally everything,” Tizard said. “Even each other. If a big toad meets a small one, dinner is guaranteed for her.